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        <description>Back to Introduction 

Theory

Single capillary

 The concentrations in plasma, C1 and in tissue, C2, follow the following system of two differential equations in time, t, and space, x:

[Eq. 1]

 where W is the linear velocity of the tracer the sinusoidal plasma, k1 and k2 are transfer coefficients or rate constants, defining the transfer of tracer between the plasma and tissue, and k3 is the transfer coefficient of sequestration of tracer due to metabolism and/or biliary excretion.</description>
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        <dc:date>2009-08-17T13:22:14-08:00</dc:date>
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        <description>Mechanics
OneAlvLung  One Alveolus Lung Lung_RC  Lung modeled analogously as electrical RC circuit Lung_RC_Air  Lung with Concentration and non-linear compliance 2CompLung_Air  Two compartment lung with concentrations and nonlinear compliances Lutchen This model is based on Lutchen et al. A nonlinear model combining pulmonary mechanics and gas concentration dynamics. IEEE Trans. Biomed. Eng. 29: 629-641, 1982.BronchiBronchiolAlvThis model represents airway with a bronchi,a bronchioles, and a alv…</description>
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